hIL7
Nomenclature
C57BL/6JSmo-Il7tm1(hIL7)Smoc
Cat. NO.
NM-HU-190031
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
Il7
Model Description
Validation Data
Fig.1 Detection of IL7 expression in thymus by RT-PCR.
Wild type: only one band at 177 bp with primers F1/R1(mIl7);
Homozygous: only one band at 340 bp with primers F2/R2(hIL7).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of IL7 expression in thymus homogenate by ELISA.
Wild-type C57BL/6 mice (WT, female, 11 weeks old, n=3) and homozygous hIL7 knockin mice (HO, male, 9 weeks old, n=3) were administered poly(I:C) (100 μg/mouse) via intraperitoneal (i.p.) injection. After 6 hours, thymus homogenates were collected for IL7 measurement by ELISA. Human IL7 was detectable in the HO mice. Notably, the ELISA kit used exhibits cross-reactivity between human and mouse IL7 proteins.
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn moreMilestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
