hIL2
Nomenclature
C57BL/6JSmo-Il2tm3(hIL2)Smoc
Cat. NO.
NM-HU-190048
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
IL2
Model Description
Validation Data
Fig1. Detection of IL2 expression by RT-PCR.
Wild type: only one band at 255 bp with primers F2/R2(mIl2); Homozygous: only one band at 320 bp with primers F1/R1(hIL2).
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Expression of human IL2 in the Serum of IL2-HU heterozygous mice is detected by ELISA.
Fig3. Expression of murine IL2 in the Serum of IL2-HU heterozygous mice and is detected by ELISA.
Fig4. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation.
hIL2+ (but not mIL2+) cells were detectable in the homozygous hPD-L2 mice.
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