hIL2/hIL2RA
Nomenclature
C57BL/6JSmo-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Cat. NO.
NM-HU-200275
Strain State
Embryo Cryopreservation
Model Description
Validation Data
Fig1. Detection of hIL-2 expression by ELISA in the hIL-2 knockin mice (Wild type and heterozygous hIL-2 KI mice were administrated with concanavalin).
Fig2. Intracellular staining of IL-2 by FACS post stimulation with anti-mCD3/anti-mCD28 (In collaboration with CrownBio).
Fig3. IL-2RA humanized mouse expresses hlL-2RA (hCD25) on naïve Treg in blood (In collaboration with CrownBio).
Fig4. hlL-2RA is highly expressed on activated Tregs in spleen in the IL-2RA huamnzied mouse (In collaboration with CrownBio).
Fig5. hlL-2RA is highly expressed on activated NK cells in spleen in the IL-2RA humanized mouse (In collaboration with CrownBio).
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