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U-GEMMs

Toolbox of Mice

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Target Humanized Knockins

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Popular Strains

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Model Customization

Gene Editing Technology

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Genetically Engineered Type

Conventional Knockout (KO)

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Point Mutation

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Humanization

Targeted Conditional Overexpression

Random Transgene

Surgery & Preconditioning

Surgery

Preconditioning

Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

PDX

Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
Resources & Support
Resources

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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	Il10-mCherry Strain Name：C57BL/6JSmo-Il10^{em1(Kozak-mCherry-WPRE-pA)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-263596
Mouse	Il10ra-Flox Strain Name：C57BL/6JSmo-Il10ra^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-200102 Research Application：Research on ERK signal transduction and TGF-β pathway
Mouse	Il10ra-Flox/Foxp3-IRES-tdTomato-2A-Cre Strain Name：C57BL/6JSmo-Il10ra^em1(flox)Foxp3^{em3(IRES-tdTomato-2A-iCre)}^Smoc Strain State：Developing \| Cat. NO.：NM-XA-261455
Mouse	Il10ra-KO Strain Name：C57BL/6JSmo-Il10ra^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-190451 Research Application：Interleukin 10 receptor subunit alpha.Immune system related.
Mouse	Il10rb-Flox Strain Name：C57BL/6Smoc-Il10rb^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Il10rb-KO Strain Name：C57BL/6JSmo-Il10rb^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-190452 Research Application：Belong to the cytokine receptor family.Immune system related.
Mouse	Il11-2A-CreERT2 Strain Name：C57BL/6JSmo-Il11^{em1(2A-CreERT2)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-263576
Mouse	Il11-Flox Strain Name：C57BL/6JSmo-Il11^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-2109628
Mouse	Il11-KO Strain Name：C57BL/6JSmo-Il11^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-190293 Research Application：Immune-related
Mouse	Il11-KO(2) Strain Name：C57BL/6JSmo-Il11^em2Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-226115

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