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U-GEMMs

Toolbox of Mice

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Reporters

Target Humanized Knockins

Tumor Targets

Immune Checkpoints

Complements

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Spontaneous Tumor

Rare Disease

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Popular Strains

Humanized PD-1 Mice

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Model Customization

Gene Editing Technology

ES Cell Targeting

CRISPR Gene Editing

Transgene

Genetically Engineered Type

Conventional Knockout (KO)

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KO First

Knock-in (KI)

Point Mutation

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Humanization

Targeted Conditional Overexpression

Random Transgene

Surgery & Preconditioning

Surgery

Preconditioning

Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

PDX

Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
Resources & Support
Resources

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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	Mxra7-Flox Strain Name：C57BL/6Smoc-Mxra7^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Mxra7-KO Strain Name：C57BL/6JSmo-Mxra7^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-201737
Mouse	Mxra8-Flox Strain Name：C57BL/6Smoc-Mxra8^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Mxra8-KO Strain Name：C57BL/6JSmo-Mxra8^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-200381 Research Application：Therapeutic antibody target
Mouse	Myadm-Flox Strain Name：C57BL/6Smoc-Myadm^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Myadm-KO Strain Name：C57BL/6JSmo-Myadm^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-2115036
Mouse	Myb-Flox Strain Name：C57BL/6Smoc-Myb^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Myb-KO Strain Name：C57BL/6JSmo-Myb^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-190617 Research Application：This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene.
Mouse	Mybbp1a-Flox Strain Name：C57BL/6JSmo-Mybbp1a^{tm1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-210195
Mouse	Mybl1-Flox Strain Name：C57BL/6Smoc-Mybl1^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD

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