Lyve1-2A-CreERT2

Nomenclature

C57BL/6JSmo-Lyve1em2(2A-CreERT2)Smoc

Cat. NO.

NM-KI-250921

Strain State

Repository Live

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Gene Summary

Gene Symbol
Lyve1

Model Description

The 2A-CreERT2 expression cassette was knocked into the Lyve1 gene stop codon site.

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Validation Data

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Fig1. Cre mediated recombination in liver of Lyve1CreERT2/+; Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of Lyve1CreERT2/+; Rosa26tdTomato/+ mouse. 

After tamoxifen induction, tdTomato was expressed in the heart, lung, liver, stomach, salivary gland, adrenal gland, pancreas, large intestine, small intestine, ovary, muscle, skin, and vagina.

Tissues with low tdTomato expression: brain, spinal cord, brown adipose tissue, kidney, spleen, and thymus.

Tissues with no obvious expression: eyeball.(49-days old, female) (For more detailed information please contact our technical advisor.) 


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