Siglece-KO
Nomenclature
C57BL/6JSmo-Sigleceem1Smoc
Cat. NO.
NM-KO-200483
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
Siglece
Model Description
Validation Data
Fig.1 Detection of siglece expression in spleen by RT-PCR.
Wild type: one band at 392 bp with primers F1/R1(mSiglece) and one band at 366 bp with primers F2/R2(mSiglece).
Abbr. M, DNA marker; WT, wild type； HO, homozygous.
Fig.2 Detection of siglece expression in spleen by FACS.
WT mice highly expressed Siglec-E on neutrophils, with less expression on other myeloid cells, but barely on lymphocytes, whereases Siglece-KO mice lacked expression of Siglec-E on all these immune cells.
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