Enpp1-KO
Nomenclature
C57BL/6JSmo-Enpp1em2Smoc
Cat. NO.
NM-KO-200618
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
Enpp1
Model Description
Validation Data
Fig.1 Radiographic evidence of increased bone mineral density, calcification and bone fusion in Enpp1−/− mice (30 weeks, male).
Radiographs of Enpp1-/- mice show incresed bone mineral density and calcification at the joints of the hindlimb compared with wild type(*). Enpp1-/- mice also exhibit bone fusion at the joints of the hindlimb compared with wild type(#). No abnormality can be detected in Enpp1+/- mice.
Fig. 2 CT analysis of the dermal sheath of vibrissae in Enpp1-/- mice.
The CT images of a representative Enpp1-/- cranium showed calcification of the dermal sheath of vibrissae.
Fig. 3 Alizarin red staining of kidney and heart. Calcium deposits are stained red in the kidneys and hearts of Enpp1-/- mice, but not in Enpp1+/+ mice.
: Calcium deposits ; 
: Blood cell
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