pAlb-hLPA-3’UTR-pA-TG/hAPOB
Nomenclature
C57BL/6JSmo-Tgtn(pAlb-hLPA-3’UTR-pA)1Apobtm2(hAPOB)Smoc
Cat. NO.
NM-XA-242245
Strain State
Repository Live
Model Description
Validation Data
Fig.1 Detection of humanized Lp(a) complex level in the plasma of pAlb-hLPA-3’UTR-pA-TG/hAPOB dKI mice at different ages (mean±SEM).
Fig.2 Detection of (A) humanized Lp(a) complex level and (B) percentage change from baseline in the steady-state levels of Lp(a) in the serum of vehicle or Muvalaplin-treated pAlb-hLPA-3’UTR-pA-TG/hAPOB dKI mice (+/HE, n=5, mean±SEM).
Fig.3 Detection of (A) triglyceride (TG), (B) total cholesterol (T-CHO), (C) high density lipoprotein cholesterol (HDL-C) and (D) light density lipoprotein cholesterol (LDL-C) level in the blood of vehicle or Muvalaplin-treated pAlb-hLPA-3’UTR-pA-TG/hAPOB dKI mice (+/HE, n=5, mean±SEM).
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