Nf1-Flox/Dhh-Cre
Nomenclature
C57BL/6JSmo-Nf1tm1(flox)Dhhem(Kozak-Cre-WPRE-pA)1Smoc
Cat. NO.
NM-XA-242545
Strain State
Repository Live
Gene Summary
Gene Symbol
Nf1
Model Description
Validation Data
Fig.1 Nf1Flox/Flox; Dhh-Cre Spontaneous Neurofibroma Phenotypic Analysis.
Body weight change (A), Percent survival (B) and Representative image (C) of Nf1Flox/Flox; Dhh-Cre mice and C57BL/6 mice.
The results showed that death began to occur in Nf1Flox/Flox; Dhh-Cre mice on postnatal day 245, with a median survival of 310 days (including mice that were euthanized), and in all Nf1Flox/Flox; Dhh-Cre mice, coat color transitioned from black to brownish-yellow starting on postnatal day 94 and gradually deepened.
Note. 7 male, 5 female. Date of birth: 2024/10/15.
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