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Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse
hCCR1
Strain Name：C57BL/6JSmo-Ccr1tm3(hCCR1)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-190067
Research Application：Immunotherapy,cancer research,drug screening
Mouse
hCCR2
Strain Name：C57BL/6JSmo-Ccr2tm2(hCCR2)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-18026
Research Application：Immunotherapy,Cancer research,Drug screening
Mouse
hCCR4(2)
Strain Name：C57BL/6JSmo-Ccr4tm1(hCCR4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215015
Mouse
hCCR5
Strain Name：C57BL/6JSmo-Ccr5tm1(hCCR5)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-2000065
Research Application：Immunotherapy,drug screening
Mouse
hCCR7
Strain Name：C57BL/6JSmo-Ccr7tm(hCCR7)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-220284
Mouse
hCCR8
Strain Name：C57BL/6JSmo-Ccr8tm1(hCCR8) Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-190053
Research Application：Immunotherapy,cancer research,drug screening
Mouse
hCCR8(2)
Strain Name：C57BL/6JSmo-Ccr8tm3(hCCR8)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000054
Research Application：Immunotherapy,drug screening
Mouse
hCCR8(2)/hCTLA-4
Strain Name：C57BL/6JSmo-Ccr8tm3(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-220074
Mouse
hCCR8(2)/hTIGIT
Strain Name：C57BL/6JSmo-Tigittm3(hTIGIT)Ccr8tm3(hCCR8)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-220073
Mouse
hCCR8(BALB/c)
Strain Name：BALB/cJSmo-Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-2000048
Research Application：Immunotherapy,drug screening
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