Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse	hCD3EDG/hEpCAM Strain Name：C57BL/6JSmo-Cd3e^tm1(hCD3E)Cd3d^tm1(hCD3D)Cd3g^tm1(hCD3G)Epcam^{tm1(hEPCAM)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220123
Mouse	hCD3EDG/hGPC3 Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Gpc3^{tm1(hGPC3)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-XA-240037
Mouse	hCD3EDG/hPD-L1 Strain Name：C57BL/6JSmo-Cd3e^tm1(hCD3E)Cd3d^tm1(hCD3D)Cd3g^tm1(hCD3G)Cd274^{tm1(hPD-L1)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220112
Mouse	hCD3EDG/hPSMA Strain Name：C57BL/6JSmo-Cd3e^tm(hCD3E)Cd3d^tm(hCD3D)Cd3g^tm(hCD3G)Folh1^{tm(hFOLH1B)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220251
Mouse	hCD3EDG/hTPBG Strain Name：C57BL/6JSmo-Cd3e^tm1(hCD3E)Cd3d^tm1(hCD3D)Cd3g^tm1(hCD3G)Tpbg^{tm1(hTPBG)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220111
Mouse	hCD4 Strain Name：C57BL/6JSmo-Cd4^{tm1(hCD4) Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-00115 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hCD4(2) Strain Name：C57BL/6JSmo-Cd4^tm(hCD4)Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-230008
Mouse	hCD4(BALB/c) Strain Name：BALB/cJSmo-Cd4^{tm3(hCD4)/Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000053 Research Application：Immunotherapy,drug screening
Mouse	hCD40 Strain Name：C57BL/6JSmo-Cd40^{tm1(hCD40) Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-00076 Research Application：cancer research,Immunotherapy,drug screening
Mouse	hCD40(BALB/c) Strain Name：BALB/cJSmo-Cd40^{tm1(hCD40)/Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000047 Research Application：Immunotherapy,drug screening

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