Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse	hTL1A(BALB/c) Strain Name：BALB/cJSmo-Tnfsf15^{tm1(hTNFSF15)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220602
Mouse	hTLR2 Strain Name：C57BL/6JSmo-Tlr2^{tm2(hTLR2)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190066 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hTLR4 Strain Name：C57BL/6JSmo-Tlr4^{tm2(hTLR4)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000025 Research Application：Immunotherapy,drug screening
Mouse	hTLR7 Strain Name：C57BL/6JSmo-Tlr7^{tm1(hTLR7)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-18027 Research Application：Immunotherapy,Cancer research,Drug screening
Mouse	hTLR8 Strain Name：C57BL/6JSmo-Tlr8^{tm2(TLR8)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-190044 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hTLR8/hPD-1 Strain Name：C57BL/6JSmo-Tlr8^tm2(TLR8)Pdcd1^{tm1(hPDCD1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-200276
Mouse	hTLR8/Lyz2-DTREGFP Strain Name：C57BL/6JSmo-Lyz2^{tm3(IRES-DTREGFP)}Tlr8^tm2(TLR8)Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-200259 Research Application：tumor research；inmmue therapy；drug screening;myeloid cell-specific DTR mice
Mouse	hTLR9 Strain Name：C57BL/6JSmo-Tlr9^{tm1(hTLR9)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-18016 Research Application：drug screening
Mouse	hTLR9/hOX40 Strain Name：C57BL/6JSmo-Tlr9^tm1(hTLR9)Tnfrsf4^{tm3(hTNFRSF4)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190024 Research Application：Immune-related
Mouse	hTM4SF1 Strain Name：C57BL/6JSmo-Tm4sf1^{tm(hTM4SF1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-230066

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