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Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse
Mefv-hMEFV*V726A
Strain Name：C57BL/6JSmo-Mefvtm1(hMEFV-V726A)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200221
Disease Connection：familial Mediterranean fever
Mouse
NVG-hIL15
Strain Name：NOD-PrkdcscidIl2rgem1Il15(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：GM-NVG-210001
Research Application：Immunotherapy,cancer research,drug screening
Mouse
pAlb-hAPOB-Tg(V4)
Strain Name：C57BL/6JSmo-Tgtn(pAlb-hAPOB-WPRE-pA)2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-235092
Mouse
pAlb-hHGF-Tg(NMG)
Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tgtn(pAlb-hHGF-pA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-234271
Mouse
pAlb-hLPA-Tg
Strain Name：C57BL/6JSmo-Tg(pAlb-hLPA)1Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-TG-225001
Mouse
pAlb-hLPA-Tg(V2)
Strain Name：C57BL/6JSmo-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-231782
Mouse
pAlb-hLPA-Tg(V3)
Strain Name：C57BL/6JSmo-Tg(pAlb-hLPA-WPRE-pA)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-232196
Mouse
pAlb-hREN
Strain Name：C57BL/6JSmo-Apoc3tm1(pAlb-hREN-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-235088
Mouse
pAtp4b-hCLDN18.2-Tg
Strain Name：C57BL/6JSmo-Tg(pAtp4b-hCLDN18.2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220197
Mouse
pCdh16-hENPP3-Tg
Strain Name：C57BL/6JSmo-Tg(pCdh16-hENPP3)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220195
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