R26-LSL-hEZH2-IRES-Luc-2A-tdTomato

Nomenclature

C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc

Cat. NO.

NM-KI-18053

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Model Description

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.
Research Application:Tumor research; drug screening

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