hMRGPRX2(BALB/c)
Nomenclature
BALB/cJSmo-Mrgprb2tm1(hMRGPRX2)Smoc
Cat. NO.
NM-HU-234362
Strain State
Repository Live
Gene Summary
Gene Symbol
Mrgprb2
Model Description
Validation Data
Fig.1 Detection of MRGPRX2 expression in bladder by RT-PCR.
Wild type: only one band at 265 bp with primers F1/R1 (mMrgprx2);
Heterozygous: one band at 265 bp with primers F1/R1 (mMrgprx2) and one band at 383 bp with primers F2/R2 (hMRGPRX2).
Abbr. M, DNA marker; HE, heterozygous; WT, wild type.
Fig.2 Detection of hMRGPRX2 expression on mast cells in het hMRGPRX2 KI mice
Fig.3 Detection of hMRGPRX2 expression on peritoneal mast cells of WT (BALB/C) mice and hMRGPRX2(BALB/C) mice by FACS.
Leukocytes were collected from wild-type BALB/C mice (9 weeks old) and homozygous hMRGPRX2(BALB/C) humanized mice ( 9 weeks old), and analyzed by flow cytometry with anti-hMRGPRX2.
Abbr. HO, homozygous; WT, wild type.
Fig.4 Detection of hMRGPRX2 expression on peritoneal mast cells of WT(BALB/C) mice and hMRGPRX2(BALB/C) mice by FACS.
Leukocytes were collected from wild-type BALB/C mice (9 weeks old) and homozygous hMRGPRX2(BALB/C) humanized mice (9 weeks old), and analyzed by flow cytometry with anti-hMRGPRX2.
Abbr. HO, homozygous; WT, wild type.
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