hPD-L1/hLAG3

Nomenclature

C57BL/6JSmo-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc

Cat. NO.

NM-HU-00137

Strain State

Embryo Cryopreservation

Export PDF

Model Description

hPD-L1(NM-HU-00062)was crossed with hLAG3(NM-HU-00049)to generate hPD-L1/hLAG3.
Research Application:Immunotherapy,cancer research,drug screening

Validation Data

pd-l1&lag3.png


Fig1 Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. mPDL1+ and mLAG3+ were detectable in wild type (WT) C57BL/6, while hPDL1+ and hLAG3+ cells were detectable in the homozygous hPDL1/hLAG3 mice.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more