hCD3EDG/hCD19

Nomenclature

C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19tm1(hCD19)Smoc

Cat. NO.

NM-HU-220109

Strain State

Repository Live

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Model Description

hCD3EDG(NM-HU-220120) mice were crossed with hCD19(NM-HU-00110) mice to generate hCD3EDG/hCD19 mice.

Validation Data

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Fig.1 Detection of immune phenotype in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.

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Fig.2 Detection of phenotype in Peripheral blood in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.

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Fig.3 Detection of phenotype in Spleen in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.

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Fig.4 Detection of phenotype in Lymph node in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.

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Fig.5 Detection of CD3 and CD19 expression in Blood in hCD3EDG/hCD19 dKI and WT mice

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Fig.6 The Body weight of HO/HO hCD3EDG/hCD19 mice. 

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Fig.7 Detection of mIgG (A) and mIgM (B) expression in serum in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice by ELISA. (n=6)

Abbr. WT, wild type.

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Fig.8 Detection of immune phenotype in peripheral blood in HO/HO hCD3EDG/hCD19 mice.

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Fig.9 The weight of different tissues in HO/HO hCD3EDG/hCD19 mice.

Table.1 Blood routine examination in hCD3EDG/hCD19 dKI mice (n=6 /group).

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