hVEGFR2
Nomenclature
C57BL/6JSmo-Kdrtm2(hKDR) Smoc
Cat. NO.
NM-HU-00098
Strain State
Embryo Cryopreservation
Gene Summary
Gene Symbol
KDR
Model Description
Validation Data

Figure 1. Expression of mouse KDR and human KDR in C57BL/6 wild type mice and KDR-HU homozygous mice.

Figure 2:In vivo validation of anti-tumor efficacy in a B16F1 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor, demonstrating that the humanized KDR mice are a good in vivo model for validating the efficacy of drugs targeting human KDR.

Figure 3:In vivo validation of anti-tumor efficacy in a MC38 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor.
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