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U-GEMMs

Toolbox of Mice

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Popular Strains

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Gene Editing Technology

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Surgery & Preconditioning

Surgery

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Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

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Human Immune System Reconstituted Models

HuPBMC

HuHSC

Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	Gabrb3-Flox Strain Name：C57BL/6Smoc-Gabrb3^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Gabrd-Flox Strain Name：C57BL/6Smoc-Gabrd^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Gabrd-KO Strain Name：C57BL/6JSmo-Gabrd^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-200604 Disease Connection：postpartum depression
Mouse	Gabre-Flox Strain Name：C57BL/6Smoc-Gabre^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Gabre-KO Strain Name：C57BL/6JSmo-Gabre^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-190576 Research Application：This gene encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system.
Mouse	Gabrg1-2A-CreERT2 Strain Name：C57BL/6JSmo-Gabrg1^{em1(2A-CreERT2)}^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-233499
Mouse	Gabrg1-Flox Strain Name：C57BL/6Smoc-Gabrg1^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Gabrg1-KO Strain Name：C57BL/6Smoc-Gabrg1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mouse	Gabrg2-Flox Strain Name：C57BL/6JSmo-Gabrg2^{em1(flox)Smoc} Strain State：Repository Live \| Cat. NO.：NM-CKO-262438
Mouse	Gabrg2-KO Strain Name：C57BL/6JSmo-Gabrg2^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-190577 Research Application：This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. Mutations in this gene have been associated with epilepsy and febrile seizures.

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