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U-GEMMs

Toolbox of Mice

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Popular Strains

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Gene Editing Technology

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Humanization

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Surgery & Preconditioning

Surgery

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Supporting Solutions

Colony Management

Cryopreservation and Cryorecovery

Housing and Management

Genotyping Analysis

Breeding Services

Auxiliary Apparatuses

e-BLOT WB Imaging System
Pre-clinical CRO Services
Oncology Drug Efficacy Evaluation Platform

Syngeneic Models

Genetically Modified Tumor Mouse Models

GMM models of cancer

GMM-derived tumor allograft models

Xenograft mouse models

CDX

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Human Immune System Reconstituted Models

HuPBMC

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Metabolism Disease Evaluation Platform

Obesity/Diabetes Models

MASH Model

Other metabolic disease models

Hyperuricemia Models

Atherosclerosis Models

Phenylketonuria Models

Humanized Metabolic Research Model

Inflammation Disease Evaluation Platform

Inflammation/Autoimmune Disease Model

Psoriasis model

Atopic Dermatitis Model

Delayed-type hypersensitivity Model

Androgenetic Alopecia Model

Asthma Model

Pulmonary Fibrosis Model

Rheumatoid Arthritis Model

Osteoarthritis Model

Systemic Lupus Erythematosus Model

Sepsis Model

Multiple Sclerosis Model

Graft-Versus-Host Disease Model

Inflammatory Bowel Disease Model

Chronic Kidney Disease Model

Others immune-mediated inflammatory diseases model

Neurological Disease Evaluation Platform

Neurological Disease Models

Parkinson's Disease Model

Alzheimer's Disease Model

Depression Model

Pain Model

Cerebrovascular Diseases Model

Intracranial Tumor

Amyotrophic Lateral Sclerosis Model

Other Neurological Disease Models

Behavioral Research Platform

Cell Lines Service Platform

Off-the-shelf cell lines

iPSC-mediated Disease Models

Cell Line Customization Services

Ex vivo & In vitro Evaluation Service Platform

Ex vivo Pharmacodynamic Evaluation Service

In vitro Pharmacodynamic Evaluation Service

Toxicology/Pathology Service Platform

Non-GLP Toxicology Evaluation Platform

Pathology Service Platform
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U-GEMMs

The establishment of U-GEMM (yoUr Genetically Engineered Mouse Model) repository containing 6,000+ “off-shelf” proprietary sets the stage of entry into new possibilities in gene function, drug screening, and human disease research.

Mouse	Nkx2-3-KO Strain Name：C57BL/6JSmo-Nkx2-3^em1Smoc Strain State：Embryo Cryopreservation \| Cat. NO.：NM-KO-202099
Mouse	Nkx2-4-Flox Strain Name：C57BL/6Smoc-Nkx2-4^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Nkx2-4-KO Strain Name：C57BL/6Smoc-Nkx2-4^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mouse	Nkx2-5-Flox Strain Name：C57BL/6JSmo-Nkx2-5^em(flox)Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-220152
Mouse	Nkx2-5-IRES-Cre Strain Name：C57BL/6JSmo-Nkx2-5^{em1(IRES-Cre-WPRE-polyA)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-200152 Research Application：Cre recombinase tool; Nkx2.5 acts as a key transcription factor and plays essential roles for heart formation. By mating the reporter mice with Cre-expressing mice, Nkx2-5 positive cells derived from double-positive mice were permanently labeled by fluorescent protein. When crossed with mice carrying a targeted floxed alleles, this strain is useful in eliminating tissue-specific conditional expression of the gene.
Mouse	Nkx2-5-KO Strain Name：C57BL/6JSmo-Nkx2-5^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-225129
Mouse	Nkx2-6-Flox Strain Name：C57BL/6Smoc-Nkx2-6^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Nkx2-6-KO Strain Name：C57BL/6Smoc-Nkx2-6^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mouse	Nkx2-9-Flox Strain Name：C57BL/6Smoc-Nkx2-9^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD
Mouse	Nkx2-9-KO Strain Name：C57BL/6Smoc-Nkx2-9^em1Smoc Strain State：Developing \| Cat. NO.：TBD

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