hCLEC4D

Nomenclature

C57BL/6JSmo-Clec4dtm1(hCLEC4D)Smoc

Cat. NO.

NM-HU-252717

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Clec4d

Model Description

The endogenous mouse Clec4d gene was replaced by human CLEC4D gene.

Validation Data

image.png

Fig.1 Detection of human CLEC4D expression on neutrophils and monocytes in blood of WT C57BL/6 mice and HO hCLEC4D mice by FACS. Leukocytes were collected from wild-type C57BL/6 mice (male,12 weeks old) and homozygous CLEC4D humanized mice (male,12 weeks old),  analyzed by flow cytometry with anti-mCLEC4D and anti-hCLEC4D.

Abbr. HO, homozygous; WT, wild type.

8c7d292b-d03a-462d-b51a-c4b044b89753.png

Fig.2 Detection of human CLEC4D expression on macrophages in peritoneal lavage fluid of WT C57BL/6 mice and HO hCLEC4D mice by FACS. Leukocytes were collected from wild-type C57BL/6 mice (male,12 weeks old) and homozygous CLEC4D humanized mice (male,12 weeks old),  analyzed by flow cytometry with anti-mCLEC4D and anti-hCLEC4D.

Abbr. HO, homozygous; WT, wild type.


You may also like

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more