hCLEC9A

Nomenclature

C57BL/6JSmo-Clec9atm1(hCLEC9A)Smoc

Cat. NO.

NM-HU-241181

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Clec9a

Model Description

The endogenous mouse Clec9a gene was replaced by human CLEC9A gene.

Validation Data

image.png

Fig.1 Detection of CLEC9A expression in spleen and lung of 13-week-old male WT and hCLEC9A knockin mice by RT-PCR. 

Wild type: only one band at 165 bp with primers F1/R1(mClec9a);

Homozygous:  only one band at 265 bp with primers F2/R2(hCLEC9A).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCLEC9A expression in spleen in WT C57BL/6 and HO hCLEC9A mice.


You may also like

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more