hCRLF2(BALB/c)
Nomenclature
BALB/cJSmo-Crlf2tm1(hCRLF2)Smoc
Cat. NO.
NM-HU-241304
Strain State
Repository Live
Gene Summary
Gene Symbol
Crlf2
Model Description
Validation Data
Fig.1 Detection of mTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in spleen of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. mTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in wild-type mice but not in hCRLF2(BALB/C) humanized mice. Leukocytes were collected from spleen of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-mTSLPR.
Fig.2 Detection of mTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in BM of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. mTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in wild-type mice but not in hCRLF2(BALB/C) humanized mice. Leukocytes were collected from BM of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-mTSLPR.
Fig.3 Detection of mTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in blood of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. mTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in wild-type mice but not in hCRLF2(BALB/C) humanized mice. Leukocytes were collected from blood of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-mTSLPR.
;)
Fig.4 Detection of hTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in spleen of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. hTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in hCRLF2(BALB/C) humanized mice but not in wild-type mice. Leukocytes were collected from spleen of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-hTSLPR.
Fig.5 Detection of hTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in BM of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. hTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in hCRLF2(BALB/C) humanized mice but not in wild-type mice. Leukocytes were collected from BM of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-hTSLPR.
Fig.6 Detection of hTSLPR expression on T cells, Gr-1+ cells, DCs and macrophages in blood of WT BALB/C mice and HO hCRLF2(BALB/C) mice by FACS. hTSLPR was exclusively detectable on T cells, Gr-1+ cells, DCs and macrophages in hCRLF2(BALB/C) humanized mice but not in wild-type mice. Leukocytes were collected from blood of wild-type BALB/C mice (female, 6 weeks old) and homozygous hCRLF2(BALB/C) humanized mice (female, 6 weeks old), and analyzed by flow cytometry with anti-hTSLPR.
You may also like
Workshop：Progress and Advances in Preclinical immuno-Oncology Research
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreShanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
