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Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse	hTDP43-A315T Strain Name：C57BL/6JSmo-Tgtn(pPrp-hTDP-43 A315T)1Smoc Strain State：Repository Live \| Cat. NO.：NM-KI-234659
Mouse	hTFR1 Strain Name：C57BL/6JSmo-Tfrc^{tm1(hTFRC)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-215059
Mouse	hTFR1(3) Strain Name：C57BL/6JSmo-Tfrc^{tm3(hTFRC)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-230029
Mouse	hTGFB1 Strain Name：C57BL/6JSmo-Tgfb1^{tm1(hTGFB1)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-200243
Mouse	hTGFBR2(2) Strain Name：C57BL/6JSmo-Tgfbr2^{tm(hTGFBR2)Smoc} Strain State：Developing \| Cat. NO.：NM-HU-230041
Mouse	hTHPO Strain Name：C57BL/6JSmo-Thpo^{tm1(hTHPO)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000062 Research Application：Cytokine humanization model；drug screening
Mouse	hTHPO(BALB/c) Strain Name：BALB/cJSmo-Thpo^{tm1(hTHPO)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-234937
Mouse	hTHPO(NMG) Strain Name：NOD.Cg-Prkdc^scidIl2rg^em1Thpo^{tm(hTHPO)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220429
Mouse	hTIGIT Strain Name：C57BL/6JSmo-Tigit^{tm1(hTIGIT)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-00053 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hTIGIT(3) Strain Name：C57BL/6JSmo-Tigit^{tm3(hTIGIT)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-200244

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