Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse	hTNC Strain Name：C57BL/6JSmo-Tnc^tm(hTNC)Smoc Strain State：Developing \| Cat. NO.：NM-HU-230025
Mouse	hTNF-β-globin-Tg Strain Name：C57BL/6JSmo-Tgtn(hTNF-β-globin)1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-TG-233181
Mouse	hTNFa-Tg Strain Name：C57BL/6JSmo-Tgtn(hTNFa promoter-hTNFa-pA)Smoc Strain State：Repository Live \| Cat. NO.：NM-TG-200004
Mouse	hTNFR2 Strain Name：C57BL/6JSmo-Tnfrsf1b^{tm2(hTNFRSF1B)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-190010 Research Application：Immune-related
Mouse	hTNFR2(BALB/c) Strain Name：BALB/cJSmo-Tnfrsf1b^{tm(hTNFRSF1B)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220499
Mouse	hTNFR2/hFCGR2B Strain Name：C57BL/6JSmo-Tnfrsf1b^{tm2(hTNFRSF1B)}Fcgr2b^{tm3(FCGR2B)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210404 Research Application：inmmue therapy; drug screening
Mouse	hTNFR2/hIL2RA Strain Name：C57BL/6JSmo-Tnfrsf1b^{tm2(hTNFRSF1B)}Il2rat^{m1(hIL2RA)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210408 Research Application：inmmue therapy；drug screening
Mouse	hTNFR2/hPD-1 Strain Name：C57BL/6JSmo-Tnfrsf1b^{tm2(hTNFRSF1B)}Pdcd1^{tm1(hPDCD1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210407 Research Application：inmmue therapy; drug screening
Mouse	hTNFR2/hPD-1/hPD-L1 Strain Name：C57BL/6JSmo-Tnfrsf1b^{tm2(hTNFRSF1B)}Pdcd1^tm1(hPDCD1)Cd274^{tm1(hPD-L1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220041
Mouse	hTNFRSF10B Strain Name：C57BL/6JSmo-Tnfrsf10b^{tm1(hTNFRSF10B)/Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-210005 Research Application：inmmue therapy；drug screening

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