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Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse
hTSLP/hIL17RA
Strain Name：C57BL/6JSmo-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-200269
Mouse
hTTR
Strain Name：C57BL/6JSmo-Ttrtm1(hTTR)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-225087
Mouse
hTTR-V30M(p.V50M)
Strain Name：C57BL/6JSmo-Ttrtm(hTTR-V50M)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220587
Mouse
hTWEAK/hAPRIL
Strain Name：C57BL/6JSmo-Tnfsf12/Tnfsf13tm1(hTNFSF12/hTNFSF13)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-234421
Mouse
hUGT1A1
Strain Name：C57BL/6JSmo-Ugt1a1tm1(hUGT1A1)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-232902
Mouse
huHSC-(NMG)
Strain Name：huHSC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017
Research Application：Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study
Mouse
huPBMC-(NMG)
Strain Name：huPBMC-(M-NSG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015
Research Application：Infectious disease; Gene therapy;Hematopoiesis; Drug targets without cross-reactivity; Immunogenicity study
Mouse
hVEGFA
Strain Name：C57BL/6JSmo-Vegfatm2(hVEGFA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000028
Research Application：Immunotherapy,drug screening
Mouse
hVEGFA(2)
Strain Name：C57BL/6JSmo-Vegfatm1(hVEGFA)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-204984
Mouse
hVEGFC
Strain Name：C57BL/6JSmo-Vegfctm(hVEGFC)Smoc
Strain State：Developing | Cat. NO.：NM-HU-230016
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