Grik4-KO

Nomenclature

C57BL/6JSmo-Grik4em1Smoc

Cat. NO.

NM-KO-190585

Strain State

Embryo Cryopreservation

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Gene Summary

Gene Symbol
Grik4

Synonyms

KA1; KA-1; GluK4; GluRgamma1; 6330551K01Rik

Chromosome

9

NCBI ID

110637

MGI ID

95817

Ensembl ID

ENSMUSG00000032017

Pubmed

Grik4

Human Ortholog

GRIK4

Model Description

Exon 5 of Grik4 gene was deleted to generate Grik4 knockout mice.
Research Application：This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.

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