SD DIO

Nomenclature

SD DIO

Cat. NO.

SR-001

Strain State

Repository Live

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Gene Summary

Model Description

The diet-induced obesity (DIO) model resembles human obesity and effectively reflects the pathogenesis of obesity in humans. It can be used to study metabolic diseases such as obesity, diabetes, and fatty liver disease.

Validation Data

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Fig.1 Body weight changes in male SD rats following high-fat diet feeding. G1 (n = 10) and G2 (n = 200) were both initiated on the diet at 6 weeks of age. Data are presented as mean ± SD. Statistical analysis was performed using an unpaired two-tailed Student’s t-test; ***p < 0.001, ****p < 0.0001; G1 vs. G2.

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