hROR1(2)

Nomenclature

C57BL/6JSmo-Ror1tm1(hROR1)Smoc

Cat. NO.

NM-HU-253302

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ror1

Model Description

The endogenous mouse Ror1 gene was replaced by human ROR1 gene.

Validation Data

df4ccec6-d333-47a4-b24b-a92512faf40a.png

Fig.1 Detection of ROR1 expression in bladder by RT-PCR. Bladder RNA was extracted from 6-week-old male wild-type C57BL/6 (WT)(n=2) and homozygous hROR1(2) knockin mice (HO) (n=2), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. 

Abbr. M, marker; HO, homozygous; WT, wild type.

d691b439-1512-4de7-b625-7e97313e1b15.png

Fig.2 Detection of ROR1 expression in hROR1(2) mice by WB. The bladder tissue lysates were collected from 6-week-old male wild-type C57BL/6 mice and 6-week-old male homozygous hROR1 mice, and then analyzed by western blot with anti-ROR1 antibody. 

Abbr. HO, homozygous; WT, wild type; PC, positive control, NIH3T3 cells.


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