hBCMA(BALB/c)
Nomenclature
BALB/cJSmo-Bcmatm1(hTNFRSF17)Smoc
Cat. NO.
NM-HU-241173
Strain State
Repository Live
Gene Summary
Gene Symbol
Tnfrsf17
Model Description
Validation Data
Fig.1 Detection of hBCMA expression on TACI+CD138+ cells in spleen of WT C57BL/6 mice and HO hBCMA(BALB/c) mice by FACS. hBCMA was exclusively detectable in hBCMA(BALB/c) humanized mice but not in wild-type mice. hBCMA was exclusively detectable on TACI+CD138+ cells in hBCMA(BALB/c) humanized mice. Leukocytes were collected from wild-type C57BL/6 mice (female, 7.6 weeks old) and homozygous hBCMA(BALB/c) humanized mice (female, 7.6 weeks old), and analyzed by flow cytometry with anti-hBCMA.
Abbr. HO, homozygous; WT, wild type.
Fig.2 Detection of hBCMA expression on TACI+CD138+ cells in bone marrow of WT C57BL/6 mice and HO hBCMA(BALB/c) mice by FACS. hBCMA was exclusively detectable in hBCMA(BALB/c) humanized mice but not in wild-type mice. hBCMA was exclusively detectable on TACI+CD138+ cells in hBCMA(BALB/c) humanized mice. Leukocytes were collected from wild-type C57BL/6 mice (female, 7.6 weeks old) and homozygous hBCMA(BALB/c) humanized mice (female, 7.6 weeks old), and analyzed by flow cytometry with anti-hBCMA .
Abbr. HO, homozygous; WT, wild type.
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