hCD79B(BALB/c)

Nomenclature

BALB/cJSmo-Cd79btm1(hCD79B)Smoc

Cat. NO.

NM-HU-241169

Strain State

Repository Live

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Gene Summary

Gene Symbol
CD79b

Model Description

The endogenous mouse Cd79b gene was replaced by human CD79B gene.

Validation Data

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Fig.1 Expression analysis of hCD79B on B cells in blood and spleen of hCD79B(BALB/c) humanized mice. 

Leukocytes were collected from blood and spleen of wild-type BALB/c mice (male, 8 weeks old) and homozygous hCD79B(BALB/c) mice (male, 6 weeks old), analyzed by flow cytometry with anti-mCD79B and anti-hCD79B. The mCD79B were exclusively detectable in wild-type mice but not hCD79B humanized mice. hCD79B were exclusively detectable in hCD79B humanized mice but not in wild-type mice.


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