hITPRIPL1

Nomenclature

C57BL/6JSmo-Itpripl1tm1(hITPRIPL1)Smoc

Cat. NO.

NM-HU-241220

Strain State

Embryo Cryopreservation

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Gene Summary

Gene Symbol
Itpripl1

Model Description

The endogenous mouse Itpripl1 gene was replaced by human ITPRIPL1 gene.

Validation Data

image.png

Fig.1 Detection of ITPRIPL1 expression in the mammary gland of WT C57BL/6 mice (male, 8-10 weeks old) and HO hITPRIPL1 knockin mice (male, 11 weeks old) by RT-PCR. 

Wild type: only one band at 505 bp with primers F1/R1(mItpripl1);

Homozygous: only one band at 361 bp with primers F2/R2(hITPRIPL1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human ITPRIPL1 expression in 8-10-week-old male WT mice and 11-week-old male hITPRIPL1 knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.


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