hLTBR
Nomenclature
C57BL/6JSmo-Ltbrtm1(hLTBR)Smoc
Cat. NO.
NM-HU-241682
Strain State
Repository Live
Gene Summary
Gene Symbol
Ltbr
Model Description
Validation Data
Fig.1 Expression analysis of hLTBR and mLTBR on macrophages and DCs in spleen of hLTBR humanized mice.
Leukocytes were collected from wild-type C57BL/6 mice (female, 8 weeks) and homozygous hLTBR mice (female, 8 weeks), and analyzed by flow cytometry with anti-mouse LTBR and anti-human LTBR. hLTBR were exclusively detectable in LTBR humanized mice but not in wild-type mice.
Fig.2 Expression analysis of hLTBR and mLTBR on macrophages and DCs in blood of hLTBR humanized mice.
Leukocytes were collected from wild-type C57BL/6 mice (female, 8 weeks) and homozygous hLTBR mice (female, 8 weeks), and analyzed by flow cytometry with anti-mouse LTBR and anti-human LTBR. hLTBR were exclusively detectable in LTBR humanized mice but not in wild-type mice.
Fig.3 Expression analysis of hLTBR and mLTBR on macrophages and DCs in bone marrow (BM) of hLTBR humanized mice.
Leukocytes were collected from wild-type C57BL/6 mice (female, 8 weeks) and homozygous hLTBR mice (female, 8 weeks), and analyzed by flow cytometry with anti-mouse LTBR and anti-human LTBR. hLTBR were exclusively detectable in LTBR humanized mice but not in wild-type mice.
You may also like
Workshop：Progress and Advances in Preclinical immuno-Oncology Research
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreShanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreCustomizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
Learn more
