Kit-V831M(NMG)
Nomenclature
NOD.Cg-PrkdcscidIl2rgem1Kitem1(V831M)Smoc
Cat. NO.
NM-KI-242813
Strain State
Repository Live
Model Description
Validation Data
Fig.1 Detection of Kit expression in the lung and spleen by RT-PCR. The point mutation of Kit has been verified by sequencing.
Wild type and Homozygous: one band at 375 bp with primers F1/R1(mKit) and one band at 123 bp with primers F/R(mGapdh).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig 2. Sanger sequencing confirms the KIT V831M mutation. The red boxes highlight a heterozygous G>A mutation (overlapping G and A peaks) in both lung and spleen samples, leading to the Valine-to-Methionine substitution at codon 831.
Table 1. Blood routine test results of Kit-V831M(NMG) and NMG mice.(Data are presented as mean and ± SEM, t-test).
For huHSC immune reconstitution data, refer to huHSC-(Kit-V831M NMG) NM-HU-263011. Click below for details.
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