Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse	hIL2RA/hIL2RG Strain Name：C57BL/6JSmo-Il2rg^tm1(IL2RG)Il2ra^{tm1(hIL2RA)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220144
Mouse	hIL2RB Strain Name：C57BL/6JSmo-Il2rb^{tm1(hIL2RB)/Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-2000055 Research Application：Cytokine humanization model；drug screening
Mouse	hIL2RB/hPD-1 Strain Name：C57BL/6JSmo-Il2rb^tm1(hIL2RB)Pdcd1^{tm1(hPDCD1)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-220036
Mouse	hIL2RG Strain Name：C57BL/6JSmo-Il2rg^{tm1(IL2RG)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-200007 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hIL2RG/hIL2RB Strain Name：C57BL/6JSmo-Il2rg^tm1(IL2RG)Il2rb^{tm1(hIL2RB)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-210354 Research Application：inmmue therapy；drug screening
Mouse	hIL3 Strain Name：C57BL/6JSmo-Il3^{tm1(hIL3)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190009 Research Application：Immune-related
Mouse	hIL3(NMG) Strain Name：NOD.Cg-Prkdc^scidIl2rg^em1Il3^{tm4(hIL3)/Smoc} Strain State：Repository Live \| Cat. NO.：NM-NSG-007 Research Application：Immunotherapy,drug screening
Mouse	hIL3-hCSF2-Tg(NMG) Strain Name：NOD-Prkdc^scidIl2rg^em1Tg(hIL3-hCSF2)Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-215006
Mouse	hIL3/hCSF2 Strain Name：C57BL/6JSmo-Il3^tm3(hIL3)Csf2^{tm3(hCSF2)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-190065 Research Application：Immunotherapy,cancer research,drug screening
Mouse	hIL3/hCSF2(BALB/c) Strain Name：BALB/cJSmo-Il3^tm(hIL3)Csf2^{tm(hCSF2)Smoc} Strain State：Embryo Cryopreservation \| Cat. NO.：NM-HU-230358

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