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Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mouse
hIL3/hCSF2(NMG)
Strain Name：NOD.Cg-PrkdcscidIl2rgem1Il3tm(hIL3)Csf2tm(hCSF2)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-220434
Mouse
hIL31
Strain Name：C57BL/6JSmo-Il31tm2(IL31)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-200008
Research Application：Immunotherapy,cancer research,drug screening
Mouse
hIL33
Strain Name：C57BL/6JSmo-Il33tm2(hIL33)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000069
Research Application：Cytokine humanization model；drug screening
Mouse
hIL34-Tg(NMG)
Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL34)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-KI-220431
Mouse
hIL36A/hIL36B/hIL36G
Strain Name：C57BL/6JSmo-Il1f6tm(hIL36A)Il1f8tm(hIL36B)Il1f9tm(hIL36G)Smoc
Strain State：Developing | Cat. NO.：NM-HU-220449
Mouse
hIL4
Strain Name：C57BL/6JSmo-Il4tm3(hIL4)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-190071
Research Application：Immunotherapy,cancer research,drug screening
Mouse
hIL4-Tg(NMG)
Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-KI-215004
Mouse
hIL4-Tg(NMG)(2)
Strain Name：NOD.Cg-PrkdcscidIl2rgem2Tg(hIL4)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220132
Mouse
hIL4/hIL4R
Strain Name：C57BL/6JSmo-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Research Application：Immunotherapy,cancer research,drug screening
Mouse
hIL4/hIL4R(BALB/c)
Strain Name：BALB/cJSmo-Il4tm3(hIL4)Il4ratm1(hIL4RA)Smoc
Strain State：Embryo Cryopreservation | Cat. NO.：NM-HU-220167
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